https://www.selleckchem.com/pr....oducts/Flavopiridol.
The stiffnesses, β-structures, hydrogen bonds, and vibrational modes of wild-type collagen triple helices are compared with osteogenesis imperfecta-related mutants using integrative structural and dynamic analysis via molecular dynamics simulations and Markov state models. Differences in these characteristics are strongly related to the unwound structural states in the mutated regions that are specific to each mutation.A novel 3,3'-bipyrazolo[1,5-a]pyridine molecular scaffold was obtained as a product of serendipity. Both photophys
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