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17 months compared to 5.77 months in the chemotherapy group. Univariate and multivariate analyses in the matched population also showed treatment with combined ablation-chemotherapy was an independent prognostic factor (P less then 0.05).Conclusions For patients with liver metastases from pancreatic cancer, the combined use of thermal ablation and systemic chemotherapy offers a chance for a better survival outcome. Due to emerging resistance to the first-line artemisinin-based antimalarials and lack of efficient vaccines and limited chemot