What Causes Trucking Accidents? Trucks make up a tiny percent of the vehicles on road however, they can be extremely dangerous and cause serious injury or even death. Accidents involving large trucks may be caused by drivers who are distracted or fail to watch their blind spots. Driver fatigue is also a factor in trucking accidents. These drivers typically work for long hours without rest breaks to meet their quotas. Driver Error Trucking accidents are the result of driver error, which is a serious problem. Driver errors can be caused by a va