https://harminechemical.com/pr....ogression-of-the-non
Aldosterone receptor, mineralocorticoid receptor (MR), is elevated in stroma in mid-secretory endometrium. In vitro, MR normally triggered by aldosterone during decidualization. Activated MR initiates LKB1 expression, followed closely by phosphorylating of AMPK that stimulates PDK4 expression. The impact of PDK4 on decidualization is independent on PDHE1α inactivation. Based on co-immunoprecipitation, PDK4 interacts with p-CREB to stop its ubiquitination for facilitating
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