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Here , we investigated the contribution of neuronal migration dysregulation to anesthesia-induced neurotoxicity into the fetal mind. Pregnant C57BL/6 mice at embryonic time 14.5 got 2.5% sevoflurane everyday for two times. Cortical neuron migration and axon lengths were assessed using GFP immunostaining. Morris water maze tests had been done to evaluate the effects of sevoflurane publicity on spatial memory in offspring. We found that sevoflurane exposure reduced axon length and caused cognitive prob
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