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Increasing research in humans and rats demonstrates that supplement D consumption is very important for attaining ideal aerobic function. The purpose of this study was to research whether calcitriol, a working kind of supplement D, improves autonomic and aerobic purpose in hypertensive rats and whether PVN oxidative stress and swelling take part in these useful impacts. Male spontaneously hypertensive rats (SHR) and normotensive control Wistar Kyoto (WKY) rats were treated with either calcitriol (40 ng/day) or veh