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https://fkbpsignal.com/index.p....hp/standardization-t
In this work, we provide a novel non-Ohmic homogenization model (NOHM) of cardiac conduction that works to tissue-scale simulations. Utilizing non-linear homogenization theory, we develop a conductivity design that effortlessly upscales the voltage-dependent conductance of space junctions, without the necessity of clearly modeling gap junctions. The NOHM design enables the simulation of electrical propagation in tissue-level cardiac domains that precisely resemble that of cell-based microscopic desig