https://her2-signaling.com/ind....ex.php/novel-sunprot
We show that germ cell-specific BAF knockdown causes phenotypes that mirror emerin/otefin mutants. Loss of BAF disrupts NL framework, obstructs differentiation and promotes germ cell loss, phenotypes which are partially rescued by inactivation associated with the ATR and Chk2 kinases. These information declare that, comparable to emerin/otefin mutants, BAF exhaustion activates the NL checkpoint that triggers germ mobile reduction. Taken collectively, our results offer ev
Like
Comment
Share
