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The evolved model was validated in advance, against fixed-bed dynamic adsorption experimental results, for pure element and binary mixtures. Then your SMB experiments were done, and purities of the Mb on the extract and BSA on the raffinate streams were 98% and 96%, respectively. The accomplished recoveries were 80% of Mb regarding the extract and 94% of BSA from the raffinate. Lastly, productivities of 6.4 gprotein⋅lads-1⋅day-1 for the extract and 28.8 gprotein⋅lads-1⋅day-1 for the raffi