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The outcomes revealed that the rate of endothelialization of the nanocomposite scaffold after 7 days of in vitro cell culture was 1.5 times and the rate of degradation of the nanocomposite film was 2 times after 8 weeks of immersion scaffolds in PBS compared to the polyurethane scaffolds. In addition, the nanocomposite scaffold possessed good mechanical properties. Despite its high modulus, it was flexible with a 500% elongation at break.The treatment of infectious or potentially infective bone defects remains a major problem in clinical