https://aktsignals.com/index.p....hp/estimating-cusine
Making use of molecular dynamics simulations, we usually do not only test readily available X-ray structures, but we additionally observe a substantially broader CDR3 loop ensemble with various distinct kinetic minima in solution. Our outcomes strongly imply, that for given CDR3 loop sequences several canonical frameworks need to be thought to characterize the conformational variety of these loops. Our recommended principal solution frameworks could increase the repertoire of available canonical groups by
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