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CT04702412; https//clinicaltrials.gov/. ClinicalTrials.gov identifier NCT04702412; https//clinicaltrials.gov/.In order to investigate the effect of pre-loading damage on the structural performance of Carbon Fiber Reinforced Polymer (CFRP) strengthened Reinforced Concrete (R.C.) beams, experimental and Finite Element Modelling (FEM) investigation was carried out on six R.C. beams. Five of the R.C. beams were damaged up to different levels of strain in the main steel bars before Flexure CFRP strengthening. One of the R.C. beams loaded up to