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Introduction Negative demographic trends are often associated with high levels of infertility, including male. In the modern literature there are data on morphofunctional changes in various organs and tissues during inflammation of various origins, obtained in experiments on animals. At the same time, there are practically no studies on changes in the seminal glands in inflammation of different etiologies. The aim of this study is to identify the morphofunctional features of the seminal glands in the dynamics of acute infectious (staphy