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Two-way ANOVA was used to identify the effects of material and substructure design on fracture load. One-way ANOVA was used to identify significant differences of fracture load (α=.05). MC and ZL showed significantly higher fracture load than ZC (P.05). MC_A showed a significantly higher fracture load than MC_B (P.05). ZC_A exhibited the lowest Weibull modulus. FEA revealed that the maximum principal stress occurred near the loading area of the veneer. ZL displayed the lowest maximum principal stress among all the materials. ZL and MC_A exhibited mo