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003), and higher plasma brain natriuretic peptide (BNP) level (P=0.006). Multivariate Cox regression analysis showed that there were higher risks of MACE [hazard ratio (HR) 11.20, 95% confidence interval (CI) 3.18-39.52, P0.001)] and heart failure (HR 27.10, 95% CI 4.65-157.83, P0.001) in the high-level group. The present study suggested that plasma SIRT2 level is a promising biomarker to predict heart failure and MACE after AMI. The present study suggested that plasma SIRT2 level is a promising biomarker to predict heart failure and