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Pathological tumor responses were somewhat greater in the KD group, with a larger mean Dworak regression grade (p=0.072) and larger percentage of near-complete (yT0N0 or yT1N1) responses (43 versus 15%, p=0.116) that almost reached statistical significance in intention-to-treat analysis (50% versus 14%, p=0.018). In rectal cancer patients undergoing curative radiotherapy, a KD significantly reduced body weight and fat mass while preserving skeletal muscle mass. We could demonstrate a trend for KDs contributing synergistically to pathologi
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