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Early treatment focused on broad immunosuppression (high-dose corticosteroids and cyclophosphamide); nevertheless, condition remission could never be attained. After one more inflammatory focus and fundamental malignancy were omitted, the triplet of pancytopenia, temperature, and high ferritin levels indicated MAS, a bone marrow biopsy confirmed additional hemophagocytic histiocytosis. Treatment with an interleukin‑1 antagonist (anakinra) induced a fast, effective healing s