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Moreover, auranofin paid down the burden of intracellular N. gonorrhoeae by over 99% outperforming the medicine of preference ceftriaxone. Auranofin had been discovered more advanced than ceftriaxone in decreasing the secretion regarding the pro-inflammatory cytokine IL-8 by endocervical cells infected with N. gonorrhoeae. Moreover, auranofin exhibited a prolonged post-antibiotic effect over 10 h, as well as incapacity to come up with resistant mutants. Overall, the current study