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KEY RESULTS In 2-3 week old pets, sumatriptan decreased the amplitude of evoked EPSCs and this ended up being greater in pieces from CFA, when compared with saline-injected rats. In CFA-injected creatures, sumatriptan enhanced the paired-pulse ratio of evoked EPSCs and reduced the price of natural miniature EPSCs. The 5-HT1B and 5-HT1D agonists CP93129 and PNU109291 both inhibited evoked EPSCs in CFA, but not saline-injected rats. In comparison, the 5-HT1A agonist R(+)-8-OH-DPAT inhibi