https://pemetrexedinhibitor.co....m/genomics-computati
PCP-consensus proteins were considering numerous strains of VEEV (VEEVcon) and CHIKV (CHIKVcon) or even the conserved PCPs of 24 various alphaviruses (AllAVcon). The AllAVcon was changed to add binding web sites for neutralizing antibodies of both VEEV and CHIKV strains (Mosaikcon). All four created proteins were produced solubly in E. coli and purified. They formed the β-strand core expected from experimental structures with this region regar
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