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44; 95% CrI 0.2 to 0.68 for LSG, SMD 0.56; 95% CrI 0.31 to 0.8 for LRYGB; and SMD 0.43; 95% CrI 0.06 to 0.8 for OAG. At 5years, LSG, LRYGB, and OAGB showed better HRQoL compared to control (SMD 0.92; 95% CrI 0.58 to 1.26, SMD 1.27; 95% CrI 0.94 to 1.61, and SMD 1.01; 95% CrI 0.63 to 1.4, respectively). LSG and LRYGB may lead to better HRQoL across most follow-up time points. Long-term analysis shows that bariatric intervention results in better HRQoL than non-surgical interventions. LSG and LRYGB may lead to better HRQoL across most fol