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Speckle noise reduces the image contrast significantly making the highly scattering structures boundaries difficult to distinguish. This has limited the usage of optical coherence tomography (OCT) images in clinical routine and hindered its potential by depriving clinicians from assessing useful information that are needed in disease monitoring, treatment, progression, and decision making. To overcome this limitation, we propose a fast and robust OCT image enhancement framework using non-linear statistical parametric technique. In the p