https://www.selleckchem.com/pr....oducts/cytosporone-b
On the other hand, laminin caused cytoplasmic retention of YAP in IPAH PAEC. Accordingly, silencing of COL4A5 and LAMC1, respectively, differentially affected tight junction formation and barrier integrity in both donor and IPAH PAEC. Collectively, our results highlight the importance for a well-maintained BM homeostasis. By linking changes in BM structure and composition to altered endothelial cell function, we here suggest an active involvement of the BM in IPAH pathogenesis.Background Mortal obligate RNA transcript (MORT), a lo
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