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Prevention (vaccines), biology and transmission factors associated with non-primary CMV, and the cost-effectiveness of universal screening, all demand further exploration to fully realize the ultimate goal of preventing cCMV. In the meantime, prevention of primary infection during pregnancy should be championed to all by means of hygiene education. Copyright © 2020 Lazzarotto, Blázquez-Gamero, Delforge, Foulon, Luck, Modrow and Leruez-Ville.Fetal to neonatal transition entails cardiorespiratory, hemodynamic, and metabolic changes coinc