https://www.selleckchem.com/pr....oducts/alkbh5-inhibi
The gut microbiome protects the host from infection by promoting epithelial integrity and providing basal immunologic stimulation. Disruption of this delicate ecosystem is linked to morbidity and mortality among critically ill patients, but the impact of traumatic injury on the gut microbiome is poorly understood. This study sought to identify alterations in gut microbiota following trauma and persistent stress in rodents without confounding antibiotics. Male Sprague-Dawley rats aged 9 weeks to 11 weeks were randomized to nai