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59, 95%CI 0.35-0.89), rs3826169 GG genotype (OR=0.59, 95%CI 0.35-0.88), and rs74245270 GA genotype (OR=0.69, 95%CI 0.49-0.98), GA or AA genotype(OR=0.70, 95%CI 0.50-0.97) had reduced risk of GDM. However, pregnant women who carried the rs74018601 GA genotype (OR=1.51, 95%CI 1.07-2.12), GA or AA genotype (OR=1.46, 95%CI 1.06-2.02), rs7205009 AA genotype (OR=1.83, 95%CI 1.18-2.86), GA or AA genotype (OR=1.53, 95%CI 1.08-2.19), and rs9888758 AG genotype (OR=1.43, 95%CI 1.02-2.0 had elevated risk of GDM. Conclusion The polymorphisms of FTO