7 week ago - Translate

https://www.selleckchem.com/pr....oducts/chir-98014.ht
Wnt/β-catenin signaling has been implicated in the terminal asymmetric divisions of neuronal progenitors in vertebrates and invertebrates. However, the role of Wnt ligands in this process remains poorly characterized. Here we used the terminal divisions of the embryonic neuronal progenitors in C. elegans to characterize the role of Wnt ligands during this process focusing on a lineage that produces the cholinergic interneuron AIY. We observed that during interphase the neuronal progenitor is elongated along the anteroposterior axis,