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Apoptosis took place vascular endothelial cells across the tresses follicle. Also, baldness had been exacerbated by briefly enhancing vascular permeability with histamine. In conclusion, cyclophosphamide caused a decrease in vascular thickness and an increase in vascular permeability; consequently, enhanced vascular permeability could be one of several causes of chemotherapy-induced alopecia. This article is shielded by copyright laws. All rights reserved.I