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uscles due to an increase in expressions of MYF6, MyoG, FABP4, and LPL gene. Current guidelines for prophylactic resection of ascending aortic aneurysms are based on post-dissection aortic diameter. However, this may not reflect the diameter prior to dissection. Pre- and post-dissection aortic diameters were compared in 34 patients with available computerised tomography scans. The median time interval between these scans was 536 days (interquartile range 354 - 1237). There was a statistically significant difference in diameters from the