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https://azd8330inhibitor.com/p....resent-observations-
Our results show that Aβ binds POPC bilayers, and that binding increases (ΔG of binding decreases) with GM1, but only as much as 3 molper cent of the ganglioside, bigger concentrations appearing to own a lower effect. MD and Langmuir balance measurements concur in showing that the peptide adsorbs on the bilayer area, but does not become inserted into it at surface pressures compatible with the cellular membrane layer conditions. Thioflavin T measurements agree with MD in revealing a tremendo