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Evidence acquisition We conducted a PubMed search for the current English-language articles coping with thyroid nodule management. Proof synthesis The initial assessment includes an evaluation of clinical danger aspects and sonographic examination of the throat. Sonographic risk-stratification systems (e.g., Thyroid Imaging Reporting and Data Systems [TIRADS]) can be used to calculate the possibility of malignancy additionally the significance of biopsy based on nodule features and size. Whene