https://www.selleckchem.com/pr....oducts/ipilimumab.ht
However, a panel of cell surface makers correlated well with ex vivo prediction of venetoclax response in 21 patient samples and may serve as biomarker independent of t(11;14). ATAC-seq of myeloma cell lines also identified an epigenetic program in venetoclax sensitive cells that was more similar to B cells than that of venetoclax resistant cells, as well as enrichment for bZIP binding motifs such as the BATF transcription factor. Together these data indicate remnants of B cell biology are associated with BCL2 dependency and point to
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