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Registered on 6 February 2018. Acupuncture-Moxibustion Clinical Trial Registry ChiCTR1800014988 . Registered on 6 February 2018. The preoperative diagnosis of periprosthetic joint infection (PJI) in patients undergoing re-revision arthroplasty is crucial, so we evaluated whether plasma levels of D-dimer and fibrin degradation product (FDP) could aid such diagnosis. We retrospectively analyzed data on patients who underwent re-revision hip or knee arthroplasty at our institute during 2008-2020. Patients were stratified into those who expe