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SRN was detected in 68.8% of the patients. High Kellgren-Lawrence scores (P=.027), presence of synovitis in the 1st CMC joint (P=.003), and increased cross-sectional area of the 1st extensor compartment of wrist (P=.005) were found to be independent risk factors for reduced superficial radial nerve conduction velocity. Sensory symptoms in patients with HOA might be due to the involvement of the superficial branch of the radial nerve. Sensory symptoms in patients with HOA might be due to the involvement of the superficial branch of the ra