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64% at 24hours and 11.8% on day 7. After intramyocardial injection, vector expression peaked on day 7 with Anc80L65; however, with adeno-associated virus, serotype 9 the peak expression was during week 6. Administration of Anc80L65 demonstrated significantly more efficient expression of reporter gene than after adeno-associated virus, serotype 9 at 6weeks (6.81±0.64 log gc/100ng DNA vs 6.49±0.28 log gc/100ng DNA, P.05). These results were consistent with the amount of genome copy per cell observed in the heart. Anc80L65 vector allow