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Treatment with 3-MA or CQ upregulated clinical scores, pathological changes, and the expression of CXCL-1, IL-1β, HMGB1, IL-18, and TNF-α except IL-10. The morphology of PMNs had been altered and PMN recruitment was increased in mice corneas treated with 3-MA or CQ, whereas rapamycin reduced the inflammatory reaction to keratitis. These results had been statistically significant. Conclusions A. fumigatus illness boosts the phrase of autophagy in corneas. Autophagy plays an anti-inflammato