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As a consequence, bone metastasis is reduced after experimental inhibition of AKT. In summary, AKT signaling could be a promising therapeutical approach for patients with bone metastases of solid tumors.Multimodal medical image fusion aims to fuse images with complementary multisource information. In this paper, we propose a novel multimodal medical image fusion method using pulse coupled neural network (PCNN) and a weighted sum of eight-neighborhood-based modified Laplacian (WSEML) integrating guided image filtering (GIF) in non-subsam
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