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The aim of this study was to investigate the effects of bivalirudin on endothelial cell proliferation and neointimal hyperplasia in a rabbit carotid artery model. "New Zealand rabbits (n = 12)" weighing 2-3kg were randomly divided into two groups. Arteriotomy was performed to the rabbit carotid artery and closed with continuous suture technique. Group B (n = 6) as a control group received 150U/kg heparin sodium; however, group A (n = 6) was given 0.75mg/kg bivalirudin i.v. bolus and infusion 1.75mg/kg/hour (B01AE06-Bivalirudin 250mg) dur
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