https://www.selleckchem.com/pr....oducts/sb-204990.htm
Our findings shed light on new mechanisms for how mechanical force regulates the biology of exosomes and bone metabolism.In a recent publication in Nature, Fane et al. establish WNT5A as a central, age-sensitive regulator of the dormancy-to-reactivation axis of melanoma. They show that aged fibroblasts in the lungs suppress WNT5A signaling induced at the primary tumor site to awaken dormant melanoma cells and promote the outgrowth of metastases.In contrast to normal type I collagen (Col1) heterotrimer (α1/α2/α1) produced by fibroblast
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