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Parameters were extracted from each ROI using the GLCM algorithm, which is widely used in ultrasound image analysis. When each parameter was extracted from the three areas, a total of 57 GLCM parameters were extracted. Finally, a total of 58 parameters were used by adding information on the size of the kidney, which is important for the diagnosis of chronic kidney disease. The artificial neural network (ANN) was composed of 58 input parameters, 10 hidden layers, and 3 output layers (normal, mild and moderate CKD, and severe CKD). Using th