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Isotretinoin-related side-effects included lip dryness, telogen effluvium, and malaise.Limitations Small sample size and destroyed to follow-up.Conclusion Isotretinoin combined with topical treatments is a far more effective than monotherapy with clobetasol and tacrolimus for FFA.Clinical Trial Code (IRCT.ir) IRCT2017091736173N1.Lumbar spondylosis, though mainly does occur at pars interarticularis of vertebrae, it hardly ever does occur at articular processes. Such as the people in