https://poziotinibinhibitor.co....m/down-regulation-as
We studied POMC and AgRP axonal projections into the hypothalamic paraventricular (PVH), lateral (LHA) and dorsomedial (DMH) nuclei in leptin receptor (LepR)-deficient mice (Leprdb/db), GH-deficient mice (Ghrhrlit/lit) plus in mice holding specific ablations of GH receptor (GHR) in a choice of LepR- or AgRP-expressing cells. Leprdb/db mice presented reduction into the density of POMC innervation to the PVH when
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