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The purpose of this research would be to determine the consequence of VitK3 and ultraviolet radiation B (UV on oxidative damage, proliferation and apoptosis of A431 cells. Practices CCK-8 assay had been utilized to detect cell expansion; Hoechst staining, TUNEL assay and flow cytometry evaluation were utilized to detect apoptosis. Western Blot ended up being perfomed to measure the phrase of apoptosis-related proteins. Flow cytometry analysis had been employed to detect the reactive air species (ROS) l