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Multiple applications of nanotechnology is expected to be helpful in preventive and diagnostic measures, immune response modulation and immunity boosters along with projecting a pathway for industry and academic researchers for addressing such pandemic. Atherosclerosis (AS) is an important pathological basis for the occurrence of coronary atherosclerotic disease (CAD), stroke and other adverse cardiovascular events. AS is an inflammatory disease, and macrophages are the main inflammatory cells in AS lesions, playing a leading role in the