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6%) in Group C (P  0.05). Lidocaine coinfusion could effectively alleviate vascular pain induced by hypertonic saline infusion. Chinese Clinical Trial Registry, number ChiCTR1900023753 . Registered on 10 June 2019. Chinese Clinical Trial Registry, number ChiCTR1900023753 . Registered on 10 June 2019. The differentiation of bone marrow mesenchymal stem cells is a complex and dynamic process. The gene expression pattern and mechanism of different periods of adipogenic and osteogenic differentiation remain unclear. Additionally, the i