https://www.selleckchem.com/pr....oducts/smoothened-ag
The concept of a Sheffer operation known for Boolean algebras and orthomodular lattices is extended to arbitrary directed relational systems with involution. It is proved that to every such relational system, there can be assigned a Sheffer groupoid and also, conversely, every Sheffer groupoid induces a directed relational system with involution. Hence, investigations of these relational systems can be transformed to the treatment of special groupoids which form a variety of algebras. If the Sheffer operation is also
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