https://www.selleckchem.com/pr....oducts/glutathione.h
01). Cell viability dramatically recovered (P less then 0.01), and the SOD activity is hugely increased (P less then 0.01) after SPPA treatment. In contrast, contents of ROS, MDA, and NO decreased sharply (P less then 0.01), and significant dose-response relationships are characterized. Moreover, the H2O2 treatment group showed significantly downregulated expression of SIRT1 (P less then 0.01) but significantly upregulated expressions of p53 and Caspase3 (P less then 0.01) compared to the control group. Following the SPPA treatment
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