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These outcomes reveal the feasibility of an innovative new approach to synthesize powerful lantibiotics with two various lipid II binding motifs to take care of specific antibiotic-resistant pathogens. Copyright © 2020 Zhao et al.Since 2012, single reduced dosage of primaquine (SLDPQ, 0.25mg/kg) is advised with artemisinin-based combination therapies, as first-line remedy for acute easy Plasmodium falciparum malaria, to interrupt its transmission, particularly in low trans