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The suggested model, as well as 2 recently-published deep understanding methods (RED-CNN and 3D-cGAN) were put on 10% and 30% dosage of 10 screening datasets, and a number of simulation datasets embedded lesions with various activities, sizes, and shapes. Besides sight evaluations, six actions such as the NRMSE, SSIM, PSNR, LPIPS, SUVmax and SUVmean were evaluated for 10 assessment datasets and 45 simulated datasets. Our S-CycleGAN method had similar SSIM and PSNR, a little hi