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A fundamental role of EUS is represented by the PDAC diagnosis. Even in this case a higher sensitivity respect to MRI and CT-scan can be observed (94% vs 79% vs 74%). The diagnostic ability could be improved by the use of ancillary techniques as elastography or contrast agents. Furthermore, with EUS it is possible to obtain a cytological or a histological specimen for the diagnosis of PDAC with low risk of adverse events and a high diagnostic accuracy. Considering therapeutic approaches, EUS can be used for pain control performing the
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